Sassafras Southern Bistro is a favorite spot in downtown Greenville for anyone who loves good Southern cooking served up in a cozy and relaxed atmosphere. Whether you’re a local or just passing through, Sassafras offers a menu full of delicious dishes that celebrate classic Southern flavors with a fresh twist.
Location and Hours
You’ll find Sassafras Southern Bistro right in the heart of downtown Greenville at 103 North Main Street, Suite 107, Greenville, SC 29601. The location is easy to reach and perfect for stopping by, whether you’re out for a casual meal or celebrating a special occasion.
The hours to visit Sassafras Southern Bistro are designed to fit nicely with dinner plans. They’re open Monday through Thursday from 5:00 PM to 9:00 PM, Friday from 5:00 PM to 9:30 PM, and Saturday from 4:30 PM to 9:30 PM. They are closed on Sundays, so it’s a great idea to plan your visit accordingly.
A Menu Full of Southern Flavors
One of the standout things about Sassafras is how well they balance traditional Southern favorites with creative dishes. The menu is wide-ranging and has something for everyone.
Start your meal with their She Crab Soup, known for its rich yet light taste and a touch of sherry that gives it a subtle kick. Another popular starter is the Fried Green Tomatoes, topped with their own homemade pimento cheese and honey mustard sauce. If you want something a bit different, try their BBQ Pulled Pork Egg Rolls, which combine smoky pork with collard greens and creamy goat cheese, blending classic Southern ingredients in a fun way.
Seafood Choices
The seafood options at Sassafras win plenty of fans. For example, the Mahi and Lump Blue Crab dish is a wonderful choice, offered grilled or blackened and served with a zesty lime cilantro butter sauce, along with creamy grits and fresh asparagus. Another top pick is the Pecan Crusted Rainbow Trout, fried and topped with a sweet apple butter that perfectly complements the crispy fish. This dish comes with mashed potatoes and green beans cooked with bacon, making it hearty and satisfying.
For the Meat Lovers
Meat lovers won’t be disappointed either. Their Sassafras Fried Chicken is one of the most talked-about dishes — crispy on the outside, juicy and tender on the inside. It’s served with Southern staples like mac and cheese that has golden, crunchy edges and roasted Brussels sprouts with a smoky bacon flavor. Also, the Filet Mignon with house-made pimento cheese or the Marinated Beef Tips with creamy parmesan risotto and asparagus are great choices for those looking for something a little more upscale.
Sides and Extras
What really makes Sassafras special is the attention they give to their sides and extras. Their mac and cheese is creamy and rich, with just the right crispy top. The Brussels sprouts have a lovely roasted depth with caramelized onions and bacon. The Pimento Cheese Fondue served with hand-cut potato chips is another crowd-pleaser, perfect as an appetizer or sharing snack.
Drinks and Atmosphere
Alongside the great food, Sassafras Southern Bistro offers a full bar with hand-crafted cocktails, local beers on tap, and a thoughtfully selected wine list. The drinks pair wonderfully with the menu and add to the overall warm and laid-back dining experience.
The atmosphere is lively without being noisy, and many guests comment on how the staff is friendly and attentive without being overbearing. It’s a place where you can relax, enjoy your company, and savor each bite without feeling rushed.
Dessert to Finish
When it’s time for dessert, be sure to try the Deep Dish Peanut Butter Pie. It’s rich and creamy, the perfect way to cap off a meal, whether you want to share it or keep it all to yourself.
Visit Sassafras Southern Bistro
Whether you’re in the mood for classic Southern flavors or a welcoming place to enjoy good company and tasty food, Sassafras Southern Bistro is an excellent choice in Greenville. The combination of delicious dishes, inviting ambiance, and great service keeps people coming back again and again.
Address:
103 North Main Street, Suite 107
Greenville, SC 29601
Hours:
Monday to Thursday: 5:00 PM – 9:00 PM
Friday: 5:00 PM – 9:30 PM
Saturday: 4:30 PM – 9:30 PM
Sunday: Closed
If you’re planning to dine there, it’s a good idea to make a reservation, especially on weekends or for larger groups. Sassafras also offers private parties and catering services tailored to your needs.
No matter when you visit, you’re sure to enjoy a warm welcome and a meal that feels like a true taste of Southern hospitality.
Sources: sassafrasbistro.com, yelp.com
Header Image Source: sassafrasbistro.com
